One of the greatest roguelikes for good reason. This is a class based 3rd person shooter where you pick up randomized items to get more powerful but the longer you take in a stage the harder the game gets. This creates a cool dynamic where you have to balance scouring the stage for items against the rising difficulty cost of doing so.

This is also a game that encourages you to break it wide open, with some runs ending because you have so many crazy effects the game crashes should you choose to continue a run long enough. That said, there are multiple endings you can go to in order to end a run and unlock things. In fact one of these endings leads to one of the coolest final stages and last boss fights I've encountered. This stage also plays some of the best music in a game insanely full of good music. Seriously, just youtube the soundtrack really quick. This game's music is in a tier of its own.

I didn't even get time to talk about coop runs, but those are also very fun.
Basically, this game is incredible and a must play for any roguelike fan.