In 25+ years I played many games with some sort of character building system. However, very few times I found one like Hades', so well balanced in abundance, variety and usefulness of skills. This couples perfectly with the roguelike(lite?) genre, as it adds a lot of unpredictability to each run.
The writing is amazing. There's no moment in the game that feels out of pace, despite the implicit repetitiveness.
Put this together with an excellent art style, great voice acting and impressive soundtrack and you got me one of the greatest games I've ever played.